(2) Departament de Medicina i Cirurgia Animals de la Universitat Autònoma de Barcelona
(3) Servei Diagnòstic de Patologia Veterinària de la Universitat Autònoma de Barcelona
Yvonne Espada Gerlach (2)
Judit Verdés Martínez (1)
Laura Martín Muñiz (1)
Albert Canturri Coll (3)
Marta Planellas Bachs (2)
Osteopetrosis is a bone dysplasia characterized by presenting osteosclerosis, an abnormal increase in bone opacity of the bone marrow. A 19-month old domestic short hair spayed female was presented for thoracolumbar pain and hind limb rigidity. Blood tests showed severe anemia, leukopenia and trombocytopenia and SNAP test for feline leukaemia virus (FeLV) and feline immunodeficiency virus (FIV) was negative. On x-rays, there was an increase in bone marrow opacity focalized at the humerus compatible with osteosclerosis. The animal was euthanized and a post-mortem long bone CT was performed and found that osteosclerosis was present also in both femurs and tibias. The necropsy confirmed osteopetrosis of long bones and revealed extramedullary haematopoiesis in several organs. The pathogeny of osteopetrosis is poorly described in veterinary medicine, especially in cats. In this particular case, the pathogeny is difficult to describe but it is most likely to mirror the infantile or malign form in humans, rather than secondary to leukaemia virus or a neoplasia. In conclusion, this condition is not well understood in veterinary patients and further studies are needed to characterize its pathogeny.
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