SURGICAL RESECTION AS UNIQUE TREATMENT OF A CEREBELLAR POORLY DIFFERENTIATED GLIOMA WITHOUT SIGNS OF RELAPSE 18 MONTHS AFTER SURGERY.

Casos Clínicos

Neurología

(1) Aúna Especialidades Veterinarias

Andrea Esteban Gracia (1)

RESUMEN CORTO - SHORT SUMMARY

Gliomas are infiltrative nervous system tumours that often migrate along white matter tracts beyond the initial location, making complete surgical excision difficult, and decreasing life expectancy in affected patients.¹

A 13-year-old neutered female mongrel weighing 27kg was presented with a chronic history of incoordination and generalized tonic-clonic seizures for two months. A brain computed tomography (CT) scan showed an isoattenuating intra-axial lesion with homogeneous contrast enhancement in the left cerebellar hemisphere consistent with neoplasia, and secondary hypertensive hydrocephalus. A left occipitotemporal craniectomy was performed and all macroscopic tumour tissue was removed with histopathological diagnosis of poorly differentiated glioma. A CT scan 13 months later failed to reveal tumour regrowth; however, a pituitary mass was detected. Eighteen months post-surgery the patient remained seizure-free on antiepileptic treatment with a complete resolution of the initial neurological signs but showed left pelvic limb lameness due to cranial cruciate ligament rupture and postural reaction deficits and lumbar discomfort due to a suspected degenerative lumbosacral stenosis. The dog died 18 months after surgery of pericardial effusion due to a cardiac mass. Post-mortem examination was not granted.

Conclusion: The described case report represents an atypical case of a caudal fossa glioma excision with an exceptionally long survival time.

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