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RESUMEN CORTO - SHORT SUMMARY

Protothecosis is a rare infectious disease, which affects animals and humans, produced by Prototheca spp, unicellular achlorophyllous algae worldwide distributed. It has been described in Dogs, Cattle and less frequently in cats.

The clinical presentation is very varied. In the humans predominates the cutaneous form, being rare the systemic,which is common in dogs. Initial clinical signs in dogs are an intermittent diarrhea, with fresh blood and/or tenesmus, weight loss, most often evolving to severe neurological and ocular lesions. In most of the patients,diarrhea precedes for months the systemic spread, which occurs through hematogenic and/or lymphatic to organs such as eyes, central nerve system, myocardium, liver, bones, kidneys and skeletal muscle.

Several species of Prototheca have been described being P. zopfii and P. wickerhamii the most often diagnosed in animals and people.

The clinical diagnosis is possible by cytology or histopathology of the affected organs, although the etiological diagnosis and identification of the Prototheca spp requires the realization of culture and /or techniques of molecular biology.

Traditionally the treatment has been based on the combination of azole drugs with amphotericin B. Localized forms have a better prognosis, not so the systemic form, which is usually slow and lethal in course.

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PROTOTHECA PYOGRANULOMATOUS COLITIS IN A GIANT SCHNAUZER